Application
Control of post-partum hemorrhage
Advantages
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Convenient: easy of insertion and removable
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Infection-fighting properties: antimicrobial agents are embedded in the nonwoven matrix
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Enhanced medicinal benefits for both the mother and newborn: misoprostol can be released to help uterine contraction
Next Steps in Development
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Develop non-thrombogenic fibers of varying diameters and densities (hollow versus solid fibers)
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Determine the swelling properties of hollow fibers based on temperature and intrauterine chemical composition environment
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Develop the protocol for loading/releasing of misoprostol into first a standard polymeric matrix to be translated to selected fiber matrix from steps 1-2. 4. Screen antimicrobial agents for functionalization to the fibers