Clean Delivery Kits

to prevent maternal and neonatal infections

Prevention
Prevention
  • PREVENTION
  • DIAGNOSTIC
  • TREATMENT
  • OVERVIEW
  • TECHNOLOGY Characteristics
  • Clean Delivery Kits
    Representative Product

    GLOBAL ANNUAL DEATHS ASSOCIATED WITH NEONATAL SEPSIS, TETANUS, AND PUERPERAL INFECTIONS

    PERCENT (%)
    NUMBER

    Maternal

    20%
    51,000

    Neonatal

    2 - 20%
    60,000 - 615,000

    Stillbirth

    N/A
    N/A

    Condition
    Otherwise uncomplicated home deliveries using unclean techniques can put mothers and neonates at risk of tetanus, maternal sepsis, and neonatal sepsis. Untreated, these conditions can be life-threatening to the mother and/or child.

    Mechanism of Action
    Clean delivery kits (CDKs) for home use are designed to prevent infection by facilitating the “6 cleans” of birth: clean hands, clean perineum, clean delivery surface, clean cord cutting instrument, clean cord care, and nothing unclean introduced to the vagina. The WHO recommends a minimum of four items in CDKs: 1) soap for cleaning hands and perineum, 2) a clean plastic sheet  of 1m² as a delivery surface, 3) a clean razor blade for cutting the cord, and 4) clean cord ties. Most CDKs supplement this with pictorial instructions for use. More complex kits may include latex gloves, apron, and gauze.  CDKs are typically packaged in small paperboard boxes or sealed plastic bags, designed to be easy to carry. Depending on the region, CDKs may be fully subsidized (free), partially subsidized (and sold below cost), or more rarely, sold without subsidy as a commercial enterprise.

    Current use in High-Resource Settings
    Birth attendants typically assemble their own birth kits in high-resource settings using a combination of disposable and re-usable equipment costing hundreds of dollars.

    Application in Low-Resource Settings
    CDK availability and impact varies by geography. In Nepal, CDKs produced by Maternal and Child Health Products Pvt. Ltd. (MCHP) are widely available in rural drug shops at affordable retail prices of approximately $0.38.  UNFPA programs also support nongovernmental organizations and government traditional birth attendant training programs with CDKs. Although the formal evidence base remains relatively thin, studies across South Asia, Egypt and Tanzania have shown reduced rates of infection among mothers and neonates using CDKs. As a secondary effect, some CDK programs have noted that broad promotion of the CDK raises awareness of clean practices and the importance of antenatal care, possibly contributing to positive health behaviors not specific to the CDK.

     

    Associated Technologies in Development

    Ceramic Umbilical Cord Finger Scissors, SafeSnip

    REPRESENTATIVE DEVICES

    MAKE
    Region
    PRICE*
    FINANCING
    STATUS
    NOTES

    BKFA

    SE Asia
    $3.00
    Given
    Marketed
    Cost approx 0.71 before shipping from Australia

    UNFPA

    Global
    $1.40
    Given
    Marketed
    Widely distributed around the world

    MCHP

    Nepal
    <0.50
    Sold
    Marketed
    Sold throughout rural Nepal, >500K to in Nepal to date

    BRAC

    Bangladesh
    <0.50
    Sold
    Marketed
    Nearly 50K units/month on a continual basis

    * Prices are approximated. Actual pricing can, and will vary by marketplace and market conditions.

  • CHARACTERISTICS OF REPRESENTATIVE PRODUCT

    TECHNOLOGY CHARACTERISTICS

    OPERATIONAL PARAMETERS

    POTENTIAL OPPORTUNITIES FOR IMPROVEMENT

    SKILLS

    REQUIRED

    Intended end user
    Training required
    Time required per use
    Birth attendant, mother
    Minutes
    Minutes

    While the specific skills of use are not difficult, widespread adoption and promotion are major hurdles for CDK programs.

    ENVIRONMENT/ INFRASTRUCTURE

    Power required
    Waste collection
    Complementary technologies required
    Temperature and storage
    Maintenance
    None
    Razor blades
    None
    None
    None

    COST

    Device Cost (Approx)
    Cost/course (Approx)
    $0.10 - $1.00
    $0.10 - $1.00

    Locally procured and assembled kits tend to be more cost effective than imported ones.

    OTHER

    Portability
    Regulatory
    Efficacy
    <100g
    None, unless drugs added

    Additional devices required for impact: None

Sources: V. Hundley et al. Inventory of Disposable Kits for Use During Pregnancy and Childbirth. Immpact. March 31, 2010. PATH. Basic Delivery Kit Guide. 2001. PATH. Delivery Kit Fact Sheet. January 2008. G. Darmstadt et al. Impact of clean delivery-kit use on newborn umbilical cord and maternal puerperal infections in Egypt. J Health Popul Nutr. 2009 Dec;27(6):746-54. S Winani et al. Use of A Clean Delivery Kit and Factors Associated with Cord Infection and Puerperal Sepsis in Mwanza, Tanzania. Journal of Midwifery & Women’s Health. 2007.